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Data from the united healthcare database and a case-controlled study 6,853 infants with cardiovascular malformations and 5,753 with non-cardiovascular malformations from the national birth defects prevention study nbdps did not show an increased risk for cardiovascular malformations overall after bupropion exposure during the first trimester.

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monitor closely for adverse reactions that could indicate high bupropion or metabolite exposures see dosage and administration , clinical pharmacology .

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educate patients that wellbutrin xl contains the same active ingredient bupropion found in zyban, which is used as an aid to smoking cessation treatment, and that wellbutrin xl should not be used in combination with zyban or any other medications that contain bupropion hydrochloride such as wellbutrin sr, the sustained-release formulation, wellbutrin, the immediate-release formulation, and aplenzin, a bupropion hydrobromide formulation .

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both bupropion and naltrexone are fda approved drugs and the combination was given the name contrave by drug s developer orexigen therapeutics.

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most of the buspar world realize that the anxiety works generally the hydroxybupropion and by staring it down its together longer an what-if.

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