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Since it is impossible to predict which patients will be affected in this manner, digoxin serum concentrations should be monitored closely if oral paromomycin is added.

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Do not take this medicine with any of the following medications -alefacept -echinacea -iopamidol -live virus vaccines -metyrapone -mifepristone this medicine may also interact with the following medications -amphotericin b -aspirin and aspirin-like medicines -certain antibiotics like erythromycin, clarithromycin, troleandomycin -certain medicines for diabetes -certain medicines for fungal infections like ketoconazole -certain medicines for seizures like carbamazepine, phenobarbital, phenytoin -certain medicines that treat or prevent blood clots like warfarin -cyclosporine -digoxin -diuretics -female hormones, like estrogens and birth control pills -isoniazid -nsaids, medicines for pain inflammation, like ibuprofen or naproxen -other medicines for myasthenia gravis -rifampin -vaccines.

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In addition, caution should be exercised when administering digoxin with drugs that may cause a significant deterioration in renal function including angiotensin-converting enzyme inhibitors ace inhibitors .

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Dicyclomine may affect the absorption of other products such as levodopa, certain azole anti-fungal drugs ketoconazole, itraconazole , slowly-dissolving forms of digoxin, among others.

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