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The safety and effectiveness of actonel sodium 5 mg daily for the prevention of postmenopausal osteoporosis were demonstrated in a 2-year, double-blind, placebo-controlled study of 383 postmenopausal women within 3 years of menopause risedronate sodium 5 mg, n 129 .

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actonel is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements.

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The safety of actonel 5 mg daily in the treatment and prevention of glucocorticoid-induced osteoporosis was assessed in two randomized, double-blind, placebo-controlled multinational trials of 344 patients male 123 and female 221 aged 18 to 85 years who had recently initiated oral glucocorticoid therapy less than or equal to 3 months, prevention study or were on long-term oral glucocorticoid therapy greater than or equal to 6 months, treatment study .

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