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Although an interaction between vinblastine and methotrexate has not been reported by the manufacturer, it is prudent to consider that vinblastine may have similar interactions as those for other vinca alkaloids, including interactions with methotrexate.

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however, coadministration of rituximab with immunosuppressive dmards, like methotrexate, may result in additive immunosuppression and an increased risk of infection.

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several studies have been conducted to evaluate methotrexate given in combination with other dmards.

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ketoprofen major in general, nsaid therapy can decrease the clearance of methotrexate, resulting in elevated and prolonged serum methotrexate levels.

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adverse effects associated with the use of methotrexate can be divided into adverse drug effects and treatment effects.

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your dose of methotrexate and when you take it will depend on the condition that is being treated.
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