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Ces effets indesirables importants expliquent que la colchicine ne soit addition le premier medicament propose flood soulager la douleur.

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in man and certain other animals, colchicine can produce a temporary leucopenia that is followed by leukocytosis.

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pharmacokinetic studies evaluating changes in systemic levels of colchicine when co-administered with cyp3a4 inhibitors in healthy volunteers have been conducted with colchicine capsules.
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8 mg of colchicine administered over 1 hour was as effective as 4.

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