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In patients with moderate renal impairment baseline creatinine clearance 30 to 50 ml min , a dose reduction to 75 of the xeloda starting dose when used as monotherapy or in combination with docetaxel from 1250 mg m 2 to 950 mg m 2 twice daily is recommended see use in specific populations and clinical pharmacology .

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patients experiencing grade 2 stomatitis painful erythema, edema or ulcers of the mouth or tongue, but able to eat or greater should be instructed to stop taking xeloda immediately and to call their physician.

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